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Article

Localization of Drosophila retinal degeneration B, a membrane-associated phosphatidylinositol transfer protein.

The Journal of cell biology - 1 Sept 1993

Vihtelic T S, Goebl M, Milligan S, O'Tousa J E, Hyde D R

Abstract excerpt

The Drosophila retinal degeneration B (rdgB) mutation causes abnormal photoreceptor response and light-enhanced retinal degeneration. Immunoblots using polyclonal anti-rdgB serum showed that rdgB is a 160-kD membrane protein. The antiserum localized the rdgB protein in photoreceptors, antennae, and regions of the Drosophila brain, indicating that the rdgB protein functions in many sensory and neuronal cells. In...

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Identifiers

PMID: 8354691
DOI: 10.1083/jcb.122.5.1013
PMCID: PMC2119623

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