Article
[Identification of the locus associated with diabetic nephropathy in type 1 diabetes mellitus].
Molekuliarnaia biologiia - 1 Jan 2000
Savost'ianov K V, Chistiakov D A, Shestakova M V, Voron'ko O E, Chugunova L A, Shamkhalova M Sh, Dedov I I, Nosikov V V
Abstract excerpt
Polymorphic tetranucleotide microsatellites D3S1512, D3S1744, D3S1550, and D3S232 were used to study the association of chromosome region 3q21-q25 neighboring the angiotensin II receptor type 1 gene (AT2R1) with diabetic nephropathy (DN) in diabetes mellitus type 1 (DM1). Allele and genotype frequencies were compared for DM1 patients with (N = 39) or without (N = 62) DN. Fisher's exact test with Bonferroni's...
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