[Insulin receptor gene in an etiology of Japanese NIDDM].

Abstract excerpt

We reviewed 23 Japanese patients with mutation in the insulin receptor gene. In general, patients with two mutant alleles tend to be more severely insulin-resistant than those with one mutant allele. Most of the mutations have been identified in patients with genetic syndromes associated with ext...

Topics

• Asian People
• Diabetes Mellitus, Type 2
• Humans
• Insulin Resistance
• Japan
• Mutation
• Receptor, Insulin