Genetic segregation analysis of red blood cell (RBC) histamine N-methyltransferase (HNMT) activity.

doi:10.1002/gepi.1370100205

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Article

Genetic segregation analysis of red blood cell (RBC) histamine N-methyltransferase (HNMT) activity.

Genetic epidemiology - 1 Jan 1993

Price R A, Scott M C, Weinshilboum R M

Abstract excerpt

Methylation is an important pathway in the biotransformation of many drugs, neurotransmitters, and xenobiotic compounds. Histamine N-methyltransferase (HNMT) catalyzes the N tau-methylation of histamine and structurally related compounds. Measurement of HNMT activity in the RBC makes it possible...

Topics

Adolescent
Adult
Alleles
Erythrocytes
Family
Female
Gene Expression Regulation, Enzymologic
Gene Frequency
Genotype
Histamine N-Methyltransferase
Humans
Male
Middle Aged
Random Allocation

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