Article
Genetic segregation analysis of red blood cell (RBC) histamine N-methyltransferase (HNMT) activity.
Genetic epidemiology - 1 Jan 1993
Price R A, Scott M C, Weinshilboum R M
Abstract excerpt
Methylation is an important pathway in the biotransformation of many drugs, neurotransmitters, and xenobiotic compounds. Histamine N-methyltransferase (HNMT) catalyzes the N tau-methylation of histamine and structurally related compounds. Measurement of HNMT activity in the RBC makes it possible to access variation in the enzyme activity that may reflect differences in less accessible tissues such as brain....
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