Article
Genetics of total serum IgE levels: a regressive model approach to segregation analysis.
Genetic epidemiology - 1 Jan 1991
Meyers D A, Beaty T H, Colyer C R, Marsh D G
Abstract excerpt
The genetics of basal total serum IgE levels was investigated in 278 individuals from 42 randomly ascertained nuclear families. The data were analyzed using the regressive model approach to segregation analysis with age, sex, and a measure of skin test responsiveness as covariates in the Class D models. The best fitting model was that of recessive inheritance of high IgE levels with a gene frequency of 0.99 for...
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