Article
Endogenous histamine and cortisol levels in subjects with different histamine N-methyltransferase C314T genotypes : a pilot study.
Molecular diagnosis & therapy - 1 Jan 2006
Hon Yuen Yi, Jusko William J, Zhou Hong-Hao, Chen Guo-Lin, Guo Dong, Zhou Gan, Spratlin Vicky E, Jann Michael W
Abstract excerpt
BACKGROUND: Histamine N-methyltransferase (HNMT) catalyzes the methylation of histamine and plays an important role in histamine biotransformation in bronchial epithelium. Enzymatic activity of HNMT has been shown to be regulated by genetic factors, including polymorphisms in the HNMT gene. In this pilot study we determined endogenous levels of histamine and cortisol in plasma and whole blood samples from...
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