Article
Differential growth patterns in SCID mice of patient-derived chronic myelogenous leukemias.
Bone marrow transplantation - 1 Aug 1998
McGuirk J, Yan Y, Childs B, Fernandez J, Barnett L, Jagiello C, Collins N, O'Reilly R J
Abstract excerpt
The development of an in vivo model for the study of CML would be of significant importance in studying its biological behavior and developing novel therapeutic strategies. We examined the ability of human leukemic cells derived from patients in either chronic (CP), accelerated (AP) or blast phas...
Topics
- Adolescent
- Adult
- Animals
- Blast Crisis
- Child
- Disease Models, Animal
- Female
- Flow Cytometry
- Humans
- In Situ Hybridization, Fluorescence
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Male