Article
Detection of p53 mutations in B cell non-Hodgkin's lymphoma cell lines.
Leukemia - 1 Apr 1995
Li C C, O'Connell C D, Beckwith M, Longo D L
Abstract excerpt
The p53 tumor suppressor gene is frequently mutated within its evolutionarily conserved regions in a number of human cancers. Previous reports demonstrated mutations of this gene in both Burkitt's lymphoma and B cell chronic lymphocytic leukemia. However, dissimilar results were obtained in non-Hodgkin's lymphoma (NHL). In one study, no mutation was detected in 43 NHL tissues. A second study reported p53...
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