Detection of p53 mutations in B cell non-Hodgkin's lymphoma cell lines.

Article

Detection of p53 mutations in B cell non-Hodgkin's lymphoma cell lines.

Leukemia - 1 Apr 1995

Li C C, O'Connell C D, Beckwith M, Longo D L

Abstract excerpt

The p53 tumor suppressor gene is frequently mutated within its evolutionarily conserved regions in a number of human cancers. Previous reports demonstrated mutations of this gene in both Burkitt's lymphoma and B cell chronic lymphocytic leukemia. However, dissimilar results were obtained in non-H...

Topics

B-Lymphocytes
Base Sequence
Cell Line
DNA Primers
Genes, p53
Humans
Lymphoma, B-Cell
Molecular Sequence Data
Mutation
Polymorphism, Single-Stranded Conformational

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