Article
Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas.
Journal of virology - 1 Mar 1994
Edwards R H, Raab-Traub N
Abstract excerpt
Mutations of the p53 tumor suppressor gene are among the most common genetic alterations found in many different human malignancies, including those of the colon, lung, and breast. Alterations in wild-type p53 lead to loss of the suppressor function and thus contribute to tumorigenesis. The potential role of p53 mutations in a sampling of B-cell lymphomas, the majority of which were associated with Epstein-Barr...
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