Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas.

doi:10.1128/JVI.68.3.1309-1315.1994

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Article

Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas.

Journal of virology - 1 Mar 1994

Edwards R H, Raab-Traub N

Abstract excerpt

Mutations of the p53 tumor suppressor gene are among the most common genetic alterations found in many different human malignancies, including those of the colon, lung, and breast. Alterations in wild-type p53 lead to loss of the suppressor function and thus contribute to tumorigenesis. The poten...

Topics

Alleles
Base Sequence
Biopsy
Burkitt Lymphoma
Genes, p53
Herpesvirus 4, Human
Humans
Immunocompromised Host
Lymphoma, B-Cell
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Sequence Analysis, DNA
Sequence Deletion

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