Article
In vitro expression of the alpha-smooth muscle actin isoform by rat lung mesenchymal cells: regulation by culture condition and transforming growth factor-beta.
American journal of respiratory cell and molecular biology - 1 Jul 1993
Mitchell J J, Woodcock-Mitchell J L, Perry L, Zhao J, Low R B, Baldor L, Absher P M
Abstract excerpt
alpha-Smooth muscle actin (alpha SM actin)-containing cells recently have been demonstrated in intraalveolar lesions in both rat and human tissues following lung injury. In order to develop model systems for the study of such cells, we examined cultured lung cell lines for this phenotype. The adult rat lung fibroblast-like "RL" cell lines were found to express alpha SM actin mRNA and protein and to organize this...
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