Article
Proliferation of rat alveolar epithelial cells in low density primary culture.
American journal of respiratory cell and molecular biology - 1 Jul 1993
Leslie C C, McCormick-Shannon K, Mason R J, Shannon J M
Abstract excerpt
Alveolar type II cells proliferate to restore the alveolar epithelium after lung injury and differentiate into type I epithelial cells. A variety of factors promote rat type II cell DNA synthesis in vitro; however, only low levels of proliferation occur when type II cells are cultured at high density. We plated type II cells at low density to determine if those growth factors that stimulate thymidine...
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