Proliferation of rat alveolar epithelial cells in low density primary culture.

doi:10.1165/ajrcmb/9.1.64

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Article

Proliferation of rat alveolar epithelial cells in low density primary culture.

American journal of respiratory cell and molecular biology - 1 Jul 1993

Leslie C C, McCormick-Shannon K, Mason R J, Shannon J M

Abstract excerpt

Alveolar type II cells proliferate to restore the alveolar epithelium after lung injury and differentiate into type I epithelial cells. A variety of factors promote rat type II cell DNA synthesis in vitro; however, only low levels of proliferation occur when type II cells are cultured at high den...

Topics

Animals
Blotting, Northern
Cell Differentiation
Cell Division
Cell Line
Cells, Cultured
Culture Media
Epithelial Cells
Growth Substances
Immunohistochemistry
Mice
Phenotype
Pulmonary Alveoli
Rats
Rats, Sprague-Dawley
Surface-Active Agents
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 8338678
DOI: 10.1165/ajrcmb/9.1.64

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8338678-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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