Article
Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins.
Infection and immunity - 1 Aug 1993
Harris T O, Grossman D, Kappler J W, Marrack P, Rich R R, Betley M J
Abstract excerpt
This study examined the emetic activity of several staphylococcal enterotoxin type A and B (SEA and SEB, respectively) mutants that had either one or two amino acid residue substitutions. New sea gene mutations were constructed by site-directed mutagenesis; gene products were obtained with glycin...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Enterotoxins
- Female
- Lymphocyte Activation
- Macaca mulatta
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Staphylococcus aureus
- Structure-Activity Relationship
- T-Lymphocytes
- Vomiting