Article
Differential requirements for actin during yeast and mammalian endocytosis.
Nature cell biology - 1 Aug 2009
Aghamohammadzadeh Soheil, Ayscough Kathryn R
Abstract excerpt
Key features of clathrin-mediated endocytosis have been conserved across evolution. However, endocytosis in Saccharomyces cerevisiae is completely dependent on a functional actin cytoskeleton, whereas actin appears to be less critical in mammalian cell endocytosis. We reveal that the fundamental requirement for actin in the early stages of yeast endocytosis is to provide a strong framework to support the force...
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