Article
Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression.
Molecular and cellular biology - 1 Mar 1992
Graves R A, Tontonoz P, Spiegelman B M
Abstract excerpt
The molecular basis of adipocyte-specific gene expression is not well understood. We have previously identified a 518-bp enhancer from the adipocyte P2 gene that stimulates adipose-specific gene expression in both cultured cells and transgenic mice. In this analysis of the enhancer, we have defined and characterized a 122-bp DNA fragment that directs differentiation-dependent gene expression in cultured...
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