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Article

Unusual mutation clusters provide insight into class I gene conversion mechanisms.

Molecular and cellular biology - 1 Jul 1993

Pease L R, Horton R M, Pullen J K, Yun T J

Abstract excerpt

Genetic diversity among the K and D alleles of the mouse major histocompatibility complex is generated by gene conversion among members of the class I multigene family. The majority of known class I mutants contain clusters of nucleotide changes that can be traced to linked family members. However, the details of the gene conversion mechanism are not known. The bm3 and bm23 mutations represent exceptions to the...

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Identifiers

PMID: 8321237
DOI: 10.1128/mcb.13.7.4374-4381.1993
PMCID: PMC360000

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