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Article

Evidence for mutation showers.

Proceedings of the National Academy of Sciences of the United States of America - 15 May 2007

Wang Jicheng, Gonzalez Kelly D, Scaringe William A, Tsai Kimberly, Liu Ning, Gu Dongqing, Li Wenyan, Hill Kathleen A, Sommer Steve S

Abstract excerpt

Mutants in the Big Blue transgenic mouse system show spontaneous clustered multiple mutations with unexpectedly high frequency, consistent with chronocoordinate events. We tested the prediction that the multiple mutations seen within the lacI mutation target sometimes occur in the context of chro...

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Identifiers

PMID: 17485671
DOI: 10.1073/pnas.0610902104
PMCID: PMC1895962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17485671-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Evidence for mutation showers.PMID 17485671Read ↗

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On the origin of unusual mutations recovered from the lacI transgenic assay.Semantic proximity Read ↗

Spontaneous tandem-base mutations (TBM) show dramatic tissue, age, pattern and spectrum specificity.Semantic proximity Read ↗

Spontaneous mutation in Big Blue transgenic mice: analysis of age, gender, and tissue type.Semantic proximity Read ↗

On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice.Semantic proximity Read ↗

Spontaneous mutation frequencies and spectra in p53 (+/+) and p53 (-/-) mice: a test of the 'guardian of the genome' hypothesis in the Big Blue transgenic mouse mutation detection system.Semantic proximity Read ↗

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