Article
Analysis of the c-myc and N-ras genes in acute myelogenous leukemia cells which manifest the constitutive expression of the c-myc gene.
Anticancer research - 1 Jan 2000
Kadam P, Steele P, Li Y Q, Preisler H
Abstract excerpt
The "constitutive" expression of the c-myc gene was detected in leukemia cells obtained from 4 patients with an acute myeloid leukemia, 3 with chronic myeloid leukemia and 1 with a myelodysplastic syndrome. Studies were undertaken to determine whether or not the myc gene was rearranged or mutated...
Topics
- Acute Disease
- Base Sequence
- Blotting, Southern
- Gene Rearrangement
- Genes, myc
- Genes, ras
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukemia, Myeloid
- Molecular Sequence Data
- Mutation
- Oncogene Protein p55(v-myc)
- Proto-Oncogene Proteins p21(ras)
- RNA, Neoplasm