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Article

Aberrant p53 protein expression in cervical intra-epithelial neoplasia.

Histopathology - 1 Nov 1993

Pöllänen R, Soini Y, Vähäkangas K, Pääkkö P, Lehto V P

Abstract excerpt

We investigated aberrant p53 expression in 81 cases of cervical intra-epithelial neoplasias (CIN) using a polyclonal antibody CM-1. The presence of human papillomavirus (HPV) DNA was evaluated by in situ and dot blot hybridization. Significant (more than 1% of cells positive) p53 positivity was found in three cases (4%) of which only one contained HPV DNA. In an additional nine cases, occasional p53 staining was...

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Identifiers

PMID: 8314222
DOI: 10.1111/j.1365-2559.1993.tb00497.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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