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Article

A two-locus model for familial Alzheimer's disease?

Genetic epidemiology - 1 Jan 1993

Macciardi F, Cavallini M C

Abstract excerpt

The present findings for familial Alzheimer's disease suggest a possible linkage to gene(s) on chromosome 21 for the early onset form and to chromosome 19 for the late onset. Since these results are not unequivocal, possible alternative hypotheses include the effect of genetic heterogeneity or of an oligogenic model of segregation for FAD.

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Identifiers

PMID: 8314040
DOI: 10.1002/gepi.1370100618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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