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Article

Genetically stable temperature-sensitive mutants of Salmonella typhi induce protection in mice.

Vaccine - 1 Nov 1993

Hooke A M, Cerquetti M C, Zeligs B J, Wang Z, Hoberg K, Bellanti J A

Abstract excerpt

Temperature-sensitive (ts) mutants of Salmonella typhi were isolated following treatment with nitrosoguanidine, and characterized with respect to cut-off temperature, ts phenotype and reversion frequency. Linkage of the ts mutations to selectable chromosomal markers was established by generalized transduction with bacteriophage phage Vi I, and the appropriate antibiotic resistances were transduced into the ts...

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Source

Identifiers

PMID: 8310758
DOI: 10.1016/0264-410x(93)90166-u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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