Article
A Live Oral Fowl Typhoid Vaccine with Reversible O-Antigen Production.
Avian diseases - 1 Mar 2015
Mitra Arindam, Łaniewski Paweł, Curtiss Roy, Roland Kenneth L
Abstract excerpt
Salmonella enterica serovar Gallinarum causes fowl typhoid, recognized worldwide as an economically important disease. The current vaccine, 9R, lacks a complete O antigen, which is a Salmonella virulence factor, and, in addition, has a number of other less well characterized chromosomal mutations. For optimal efficacy, 9R is administered by injection. In an effort to develop a vaccine suitable for oral...
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