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Article

The pheromone receptors inhibit the pheromone response pathway in Saccharomyces cerevisiae by a process that is independent of their associated G alpha protein.

Genetics - 1 Dec 1993

Hirsch J P, Cross F R

Abstract excerpt

Dominant mutations at the DAF2 locus confer resistance to the cell-cycle arrest that normally occurs in MATa cells exposed to alpha-factor. One of these alleles, DAF2-2, has also been shown to suppress the constitutive signaling phenotype of null alleles of the gene encoding the alpha subunit of the G protein involved in pheromone signaling. These observations indicate that DAF2-2 inhibits transmission of the...

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Identifiers

PMID: 8307334
DOI: 10.1093/genetics/135.4.943
PMCID: PMC1205755

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The pheromone receptors inhibit the pheromone response pathway in Saccharomyces cerevisiae by a process that is independent of their associated G alpha protein.PMID 8307334Read ↗

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