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Article

Epithelial tumours induced by a herpesvirus oncogene in transgenic mice.

Oncogene - 1 Jan 1994

Murphy C, Kretschmer C, Biesinger B, Beckers J, Jung J, Desrosiers R C, Müller-Hermelink H K, Fleckenstein B W, Rüther U

Abstract excerpt

To investigate the role of herpesviral genes in tumourigenesis, transgenic mice were generated expressing STP-C, a transformation associated protein of the lymphoma inducing herpesvirus saimiri. Epithelial tumours developed in the salivary gland, pancreas, thymus and liver of transgenic mice within the first weeks of life. Thus, the target cells for tumour formation in the transgenic mice were surprisingly...

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PMID: 8302583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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