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Article

Epithelial tumours induced by a herpesvirus oncogene in transgenic mice.

Oncogene - 1 Jan 1994

Murphy C, Kretschmer C, Biesinger B, Beckers J, Jung J, Desrosiers R C, Müller-Hermelink H K, Fleckenstein B W, Rüther U

Abstract excerpt

To investigate the role of herpesviral genes in tumourigenesis, transgenic mice were generated expressing STP-C, a transformation associated protein of the lymphoma inducing herpesvirus saimiri. Epithelial tumours developed in the salivary gland, pancreas, thymus and liver of transgenic mice with...

Topics

Animals
Base Sequence
Cell Transformation, Neoplastic
Epithelium
Herpesvirus 2, Saimiriine
Lymphocyte Activation
Mice
Mice, Transgenic
Molecular Sequence Data
Neoplasms
Oncogene Proteins, Viral
Oncogenes

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PMID: 8302583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8302583-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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