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Article

Transforming growth factor‐β and bone morphogenetic protein‐2 act by distinct mechanisms to promote chick limb cartilage differentiation in vitro

1 Jun 1994

Abstract excerpt

A number of studies suggest that several members of the transforming growth factor-beta (TGF-beta) family of peptide growth factors may be involved in the regulation of cartilage differentiation. It has been previously reported that TGF-beta 1 and TGF-beta 2 promote the chondrogenic differentiation of chick limb mesenchymal cells in high density micromass cultures (Kulyk et al. [1989a] Dev. Biol. 135:424-430). In...

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PMID: 7919498
DOI: 10.1002/aja.1002000203

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