Article
Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells.
Journal of cellular physiology - 1 Apr 2010
Weiss S, Hennig T, Bock R, Steck E, Richter W
Abstract excerpt
Common in vitro protocols for chondrogenesis of mesenchymal stem cells (MSCs) induce an inadequate, hypertrophic differentiation cascade reminiscent of endochondral bone formation. We aimed to modify chondrogenic protocols in order to identify potent inducers, promotors, and inhibitors to achieve better chondrogenesis. Nine factors suspected to stimulate or inhibit chondrogenesis were used for chondrogenic in...
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