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Article

Characterization of proteoglycans synthesized by rabbit articular chondrocytes in response to transforming growth factor-beta (TGF-beta).

Biochimica et biophysica acta - 10 Jul 1991

Redini F, Daireaux M, Mauviel A, Galera P, Loyau G, Pujol J P

Abstract excerpt

The effect of transforming growth factor-beta (TGF-beta, 1 ng/ml) on proteoglycan synthesis by rabbit articular chondrocytes in culture was studied in the presence of fetal bovine serum. Exposure of confluent cells for 24 h to the factor resulted in a marked increase of 35S-labeled sulfate incorporation in the newly synthesized proteoglycans (PG), as estimated by glycosaminoglycan (GAG) radioactivity (+58%). The...

Topics

Animals
Cartilage, Articular
Cells, Cultured
Chromatography, Gel
Chromatography, Ion Exchange
Glycosaminoglycans
Kinetics
Phenotype
Proteoglycans
Rabbits
Sulfates

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transforming Growth Factor beta

Source

Identifiers

PMID: 1863600
DOI: 10.1016/0167-4889(91)90123-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1863600-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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