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Article

Probing weakly polar interactions in cytochrome c.

Protein science : a publication of the Protein Society - 1 Dec 1993

Auld D S, Young G B, Saunders A J, Doyle D F, Betz S F, Pielak G J

Abstract excerpt

Theoretical, statistical, and model studies suggest that proteins are stabilized by weakly polar attractions between sulfur atoms and properly oriented aromatic rings. The two sulfur-containing amino acids, methionine and cysteine, occur frequently among functional alleles in random mutant librar...

Topics

Cysteine
Cytochrome c Group
Cytochromes c
Guanidine
Guanidines
Magnetic Resonance Spectroscopy
Methionine
Models, Molecular
Mutation
Phenylalanine
Protein Conformation
Protein Denaturation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Thermodynamics

Tyrosine

Source

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Identifiers

PMID: 8298464
DOI: 10.1002/pro.5560021218
PMCID: PMC2142317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8298464-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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