Article
A computer simulation study of VNTR population genetics: constrained recombination rules out the infinite alleles model.
Genetics - 1 Nov 1993
Harding R M, Boyce A J, Martinson J J, Flint J, Clegg J B
Abstract excerpt
Extensive allelic diversity in variable numbers of tandem repeats (VNTRs) has been discovered in the human genome. For population genetic studies of VNTRs, such as forensic applications, it is important to know whether a neutral mutation-drift balance of VNTR polymorphism can be represented by the infinite alleles model. The assumption of the infinite alleles model that each new mutant is unique is very likely to...
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