Physical properties of VNTR data, and their impact on a test of allelic independence.

Abstract excerpt

In this article we describe the physical properties of VNTR data, as well as their effects on the two-dimensional distribution of fragment pairs. Tests of independence of alleles at a locus may confound those physical properties with allele independence. A recently proposed test by Geisser and Johnson is an example. We show that alleles can be strictly independent, yet the proposed test suggests large violations...

Topics

• Alleles
• Chi-Square Distribution
• DNA
• DNA Fingerprinting
• Electrophoresis, Agar Gel
• Forensic Medicine
• Gene Frequency
• Genetic Variation
• Genetics, Population
• Models, Genetic
• Repetitive Sequences, Nucleic Acid
• Reproducibility of Results