Discerning the function of p53 by examining its molecular interactions.

doi:10.1002/bies.950151102

Back to search

Article

Discerning the function of p53 by examining its molecular interactions.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Nov 1993

Oliner J D

Abstract excerpt

Of the many genes mutated on the road to tumor formation, few have received as much attention as p53. The gene has come to occupy center stage for the simple reason that it is more frequently altered in human tumors than any other known gene, undergoing mutation at a significant rate in almost ev...

Topics

Cell Division
DNA
DNA-Binding Proteins
Genes, p53
Humans
Mutation
Neoplasms
Transcription Factors
Transcription, Genetic
Tumor Suppressor Protein p53

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.