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Article

Effect of Deoxyribonucleic Acid Protamination on Fluorochrome Staining and in Situ Nick-Translation of Murine and Human Mature Spermatozoa1

1 Nov 1993

Abstract excerpt

A major event in enhancing sperm chromatin stability is the replacement of the histones by protamines during spermiogenesis. In this study, we present results indicating that chromomycin A3 (CMA3) can be used to show protamine deficiency in sperm chromatin. Fixed chromatin of mature mouse spermatozoa showed high fluorescence after treatment with ethidium bromide (EB), but was completely unstained after treatment...

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Identifiers

PMID: 8286574
DOI: 10.1095/biolreprod49.5.1083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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