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Article

Sperm nuclear DNA damage and altered chromatin structure: effect on fertilization and embryo development

1 Dec 1998

Abstract excerpt

In the first part of this report we investigate whether chromatin anomalies in human spermatozoa can influence fertilization after intracytoplasmic sperm injection (ICSI). We have examined the sperm chromatin packaging quality using the chromomycin A3 (CMA3) fluorochrome and the presence of DNA damage in spermatozoa using in-situ nick translation. When comparing the spermatozoa of patients undergoing in-vitro...

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Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Reproductive Biology and Fertility
Sperm and Testicular Function

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10091054
DOI: 10.1093/humrep/13.suppl_4.11

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