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Article

Relationship between the Presence of Endogenous Nicks and Sperm Chromatin Packaging in Maturing and Fertilizing Mouse Spermatozoa1

1 May 1995

Abstract excerpt

Mammalian spermiogenesis involves the replacement of histones by protamines, resulting in a highly compacted chromatin. Upon fertilization, the reverse process occurs. We have previously shown that the chromomycin A3 (CMA3) fluorochrome represents a useful tool for detecting protamine deficiency in spermatozoa. In this study we investigated CMA3 fluorochrome accessibility and the presence of endogenous nicks in...

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Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Reproductive Biology and Fertility
Sperm and Testicular Function

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 7626715
DOI: 10.1095/biolreprod52.5.1149

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Relationship between the Presence of Endogenous Nicks and Sperm Chromatin Packaging in Maturing and Fertilizing Mouse Spermatozoa1PMID 7626715Read ↗

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Chromomycin A<sub>3</sub>‐staining as an indicator of protamine deficiency and fertilizationSemantic proximity Read ↗

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