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Article

Relationship between the Presence of Endogenous Nicks and Sperm Chromatin Packaging in Maturing and Fertilizing Mouse Spermatozoa1

1 May 1995

Abstract excerpt

Mammalian spermiogenesis involves the replacement of histones by protamines, resulting in a highly compacted chromatin. Upon fertilization, the reverse process occurs. We have previously shown that the chromomycin A3 (CMA3) fluorochrome represents a useful tool for detecting protamine deficiency in spermatozoa. In this study we investigated CMA3 fluorochrome accessibility and the presence of endogenous nicks in...

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Source

Identifiers

PMID: 7626715
DOI: 10.1095/biolreprod52.5.1149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Relationship between the Presence of Endogenous Nicks and Sperm Chromatin Packaging in Maturing and Fertilizing Mouse Spermatozoa1PMID 7626715Read ↗

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