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Article

The effects of protamine deficiency on ultrastructure of human sperm nucleus

1 Jan 2014

Abstract excerpt

BACKGROUND: Chromomycin A3 (CMA3) staining is one of the staining methods for detecting protamine deficiency in sperm nucleus. CMA3 is a fluorochrome that competes with protamines for binding to DNA double helix. It has been shown in our previous studies that percentage of CMA3 positive spermatozoa in semen has a close significant relationship with the fertilization rate in in vitro fertilization (IVF). The aim...

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PMID: 24592371
DOI: 10.4103/2277-9175.124666

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