Article
Rapid HLA typing by multiplex amplification refractory mutation system.
Journal of clinical pathology - 1 Dec 1993
Patel P, Lo Y M, Bell J I, Wainscoat J S
Abstract excerpt
AIMS: To detect HLA susceptibility and protective alleles associated with insulin dependent diabetes mellitus (IDDM) using a multiplex amplification refractory mutation system (ARMS). These include DR3 and DR4 alleles at the DRB1 locus, presence or absence of aspartic acid at position 57 (Asp-57) of the DQB1 locus, and presence or absence of arginine at position 52 (Arg-52) of the DQA1 locus. METHODS: The ARMS...
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