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Article

Toxicity of phorbol esters for human epithelial cells expressing a mutant ras oncogene.

Molecular carcinogenesis - 1 Jan 1993

Dawson T, Bond J, Eccles N, Wynford-Thomas D

Abstract excerpt

Phorbol esters and related compounds provide a promising source of potential anticancer agents. The mechanism of their toxicity, however, is unclear, and interpretation has been complicated by the conflicting responses exhibited by different transformed cell lines. Previously we showed that in primary thyroid follicular cells, expression of mutant p21ras conferred a striking sensitivity to the toxic effects of...

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PMID: 8280376
DOI: 10.1002/mc.2940080411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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