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Article

Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system.

Neuron - 1 Dec 1993

Tomasiewicz H, Ono K, Yee D, Thompson C, Goridis C, Rutishauser U, Magnuson T

Abstract excerpt

N-CAM is abundantly expressed in the nervous system in the form of numerous structural variants with characteristic distribution patterns and functional properties. N-CAM-180, the variant having the largest cytoplasmic domain, is expressed by all neurons. The N-CAM-180-specific exon 18 has been d...

Topics

Actins
Aging
Animals
Base Sequence
Brain
Cell Adhesion Molecules, Neuronal
DNA Primers
Exons
Female
Gene Deletion
Genetic Variation
Genomic Library
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C57BL

Mice, Inbred Strains

Mice, Transgenic

Molecular Sequence Data

Source

Identifiers

PMID: 8274281
DOI: 10.1016/0896-6273(93)90228-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8274281-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system.PMID 8274281Read ↗

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