Article
Prion encephalopathies of animals and humans.
Developments in biological standardization - 1 Jan 1993
Prusiner S B
Abstract excerpt
Studies over the past decade of the infectious prions causing scrapie and other transmissible neurodegenerative diseases support the hypothesis that these pathogens are novel. After convincing evidence was obtained showing that scrapie infectivity depends upon a protein component, the term "prion" was introduced to distinguish these infectious pathogens from others, including viroids and viruses. Enriching...
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