Article
Analysis of nucleo-cytoplasmic transport in a thermosensitive mutant of nuclear pore protein NSP1.
European journal of cell biology - 1 Oct 1993
Nehrbass U, Fabre E, Dihlmann S, Herth W, Hurt E C
Abstract excerpt
NSP1 is related to a group of nuclear pore proteins termed 'nucleoporins'. We observe that in thermosensitive nsp1 mutants lacZ fusion proteins which contain the nuclear targeting sequence of Mat alpha 2 or Pho2 are located inside the nucleus at the permissive temperature (23 degrees C), but are...
Topics
- Biological Transport
- Calcium-Binding Proteins
- Cell Nucleus
- Cytoplasm
- Fungal Proteins
- Homeodomain Proteins
- Mutation
- Nuclear Envelope
- Nuclear Pore Complex Proteins
- Nuclear Proteins
- Recombinant Fusion Proteins
- Repressor Proteins
- Ribosomal Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Temperature
- Tetrahydrofolate Dehydrogenase
- Trans-Activators