Article
Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p.
The Journal of cell biology - 1 Jun 1996
Zabel U, Doye V, Tekotte H, Wepf R, Grandi P, Hurt E C
Abstract excerpt
The amino-terminal domain of Nic96p physically interacts with the Nsp1p complex which is involved in nucleocytoplasmic transport. Here we show that thermosensitive mutations mapping in the central domain of Nic96p inhibit nuclear pore formation at the nonpermissive temperature. Furthermore, the carboxyterminal domain of Nic96p functionally interacts with a novel nucleoporin Nup188p in an allele-specific fashion,...
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