Recessive mutations in the second largest subunit of TFIIIC suggest a new step in RNA polymerase III transcription.

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Article

Recessive mutations in the second largest subunit of TFIIIC suggest a new step in RNA polymerase III transcription.

Gene expression - 1 Jan 1995

Sethy I, Willis I M

Abstract excerpt

An analysis of mutant S. cerevisiae strains selected for their ability to increase transcription by RNA polymerase (pol) III has identified 14 isolates in which this phenotype is recessive. Genetic linkage and complementation studies suggest that all 14 isolates contain recessive alleles of PCF1....

Topics

Alleles
Base Sequence
Chromosome Mapping
Chromosomes, Fungal
Cloning, Molecular
Fungal Proteins
Genes, Dominant
Genes, Fungal
Genes, Recessive
Humans
Molecular Sequence Data
Mutagenesis, Site-Directed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA Polymerase III

Saccharomyces cerevisiae

Suppression, Genetic

Transcription Factors

Transcription Factors, TFIII

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7488859
PMCID: PMC6138035

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7488859-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Recessive mutations in the second largest subunit of TFIIIC suggest a new step in RNA polymerase III transcription.PMID 7488859Read ↗

A mutation in the second largest subunit of TFIIIC increases a rate-limiting step in transcription by RNA polymerase III.Semantic proximity Read ↗

A tetratricopeptide repeat mutation in yeast transcription factor IIIC131 (TFIIIC131) facilitates recruitment of TFIIB-related factor TFIIIB70.Semantic proximity Read ↗

The PCF1-1 mutation increases the activity of the transcription factor (TF) IIIB fraction from Saccharomyces cerevisiae.Semantic proximity Read ↗

A mutation in the C31 subunit of Saccharomyces cerevisiae RNA polymerase III affects transcription initiation.Semantic proximity Read ↗

Identification of the gene (SSU71/TFG1) encoding the largest subunit of transcription factor TFIIF as a suppressor of a TFIIB mutation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Multiple roles of the tau131 subunit of yeast transcription factor IIIC (TFIIIC) in TFIIIB assembly.Semantic proximity Read ↗

Dominant mutations in three different subunits of replication factor C suppress replication defects in yeast PCNA mutants.Semantic proximity Read ↗

Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae.Semantic proximity Read ↗

Interaction between yeast RNA polymerase III and transcription factor TFIIIC via ABC10alpha and tau131 subunits.Semantic proximity Read ↗

The sua8 suppressors of Saccharomyces cerevisiae encode replacements of conserved residues within the largest subunit of RNA polymerase II and affect transcription start site selection similarly to sua7 (TFIIB) mutations.Semantic proximity Read ↗

A suppressor of an RNA polymerase II mutation of Saccharomyces cerevisiae encodes a subunit common to RNA polymerases I, II, and III.Semantic proximity Read ↗

A suppressor of mutations in the class III transcription system encodes a component of yeast TFIIIB.Semantic proximity Read ↗

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