Article
Immunohistochemical expression of mutant p53 oncogene in transitional mucosa adjacent to human colon cancer.
Clinical and investigative medicine. Medecine clinique et experimentale - 1 Oct 1993
Baytner S, Mitmaker B, Gordon P H, Wang E
Abstract excerpt
The purpose of this study was to analyze the expression of a mutant (MUT) p53 oncogene protein in the mucosal crypts adjacent to a human colon cancer. Five 1-cm mucosal segments were taken from the surgical specimens over a 5-cm distance from the tumor. Immunohistochemistry was performed using a monoclonal antibody (Ab3) to the MUT p53 and examination by light microscopy. The mean % labelling index (LI) of 10...
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