Immunohistochemical expression of mutant p53 oncogene in transitional mucosa adjacent to human colon cancer.

Article

Immunohistochemical expression of mutant p53 oncogene in transitional mucosa adjacent to human colon cancer.

Clinical and investigative medicine. Medecine clinique et experimentale - 1 Oct 1993

Baytner S, Mitmaker B, Gordon P H, Wang E

Abstract excerpt

The purpose of this study was to analyze the expression of a mutant (MUT) p53 oncogene protein in the mucosal crypts adjacent to a human colon cancer. Five 1-cm mucosal segments were taken from the surgical specimens over a 5-cm distance from the tumor. Immunohistochemistry was performed using a...

Topics

Antibodies, Monoclonal
Cell Nucleus
Colonic Neoplasms
Gene Expression
Genes, p53
Humans
Immunohistochemistry
Intestinal Mucosa
Mutation
Tumor Suppressor Protein p53

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