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Processing and Presentation of Murine Cytomegalovirus pORF<i>m164</i>-Derived Peptide in Fibroblasts in the Face of All Viral Immunosubversive Early Gene Functions

15 Jun 2002

Abstract excerpt

CD8 T cells are the principal effector cells in the resolution of acute murine cytomegalovirus (mCMV) infection in host organs. This undoubted antiviral and protective in vivo function of CD8 T cells appeared to be inconsistent with immunosubversive strategies of the virus effected by early (E)-phase genes m04, m06, and m152. The so-called immune evasion proteins gp34, gp48, and gp37/40, respectively, were found...

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Identifiers

PMID: 12021337
DOI: 10.1128/jvi.76.12.6044-6053.2002

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