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Article

The context of gene expression defines the immunodominance hierarchy of cytomegalovirus antigens.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2013

Dekhtiarenko Iryna, Jarvis Michael A, Ruzsics Zsolt, Čičin-Šain Luka

Abstract excerpt

Natural immunity to CMV dominates the CD4 and CD8 memory compartments of the CMV-seropositive host. This property has been recently exploited for experimental CMV-based vaccine vector strategies, and it has shown promise in animal models of AIDS and Ebola disease. Although it is generally agreed that CMV-based vaccine vectors may induce highly protective and persistent memory T cells, the influence of the gene...

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Share to Antigens, Viral
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

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Share to Herpes Simplex

Share to Herpesvirus 1, Human

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Source

Identifiers

PMID: 23460738
DOI: 10.4049/jimmunol.1203173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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