Article
T cell receptor gene expression and genotypes in celiac disease.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1994
Thurley C A, Kwan W C, Freeman H J, Gilks C B
Abstract excerpt
Celiac disease (CD) occurs as a result of an abnormal immune response, within the mucosa of the small bowel, to dietary gliadin peptides. To further characterize the intramucosal lymphocytes in patients with untreated CD, we compared T cell receptor (TCR) variable region gene expression in small bowel biopsies from patients with CD to that of normal small bowel. We also assessed TCR genotypes, using restriction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
