Article
T cell receptor gene expression and genotypes in celiac disease.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1994
Thurley C A, Kwan W C, Freeman H J, Gilks C B
Abstract excerpt
Celiac disease (CD) occurs as a result of an abnormal immune response, within the mucosa of the small bowel, to dietary gliadin peptides. To further characterize the intramucosal lymphocytes in patients with untreated CD, we compared T cell receptor (TCR) variable region gene expression in small...
Topics
- Adult
- Aged
- Celiac Disease
- Female
- Gene Expression
- Genotype
- Humans
- Intestinal Mucosa
- Intestine, Small
- Male
- Middle Aged
- Polymorphism, Restriction Fragment Length
- Receptors, Antigen, T-Cell, alpha-beta