Schistosoma mansoni: genetic complementation analysis shows that two independent hycanthone/oxamniquine-resistant strains are mutated in the same gene.

doi:10.1006/expr.1993.1104

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Article

Schistosoma mansoni: genetic complementation analysis shows that two independent hycanthone/oxamniquine-resistant strains are mutated in the same gene.

Experimental parasitology - 1 Dec 1993

Pica-Mattoccia L, Dias L C, Moroni R, Cioli D

Abstract excerpt

Two drug-resistant strains of Schistosoma mansoni were compared in this study in order to decide whether they are both mutated in the same gene with respect to drug-sensitive schistosomes. One of the two strains was isolated in the laboratory, while the other one originated from a treated uncured...

Topics

Animals
Drug Resistance
Female
Genetic Complementation Test
Humans
Hycanthone
Male
Mutation
Oxamniquine
Schistosoma mansoni
Species Specificity

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