Article
Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E.
Molecular and cellular biology - 1 Dec 1993
Rosenwald I B, Lazaris-Karatzas A, Sonenberg N, Schmidt E V
Abstract excerpt
Cyclin D1 is a G1-specific cyclin that has been linked to lymphoid, parathyroid, and breast tumors. Recent studies suggested that high protein levels of cyclin D1 are not always produced when cyclin D1 mRNA is overexpressed in transfected cells, suggesting that posttranscriptional events may be i...
Topics
- 3T3 Cells
- Alleles
- Animals
- Cyclin D1
- Cyclins
- Estradiol
- Eukaryotic Initiation Factor-4E
- Genes, myc
- Genetic Vectors
- Mammary Tumor Virus, Mouse
- Mice
- Oncogene Proteins
- Peptide Initiation Factors
- Protein Processing, Post-Translational
- RNA, Messenger
- Transfection