Article
Overexpression of Cyclin E in Acute Myelogenous Leukemia
1 Nov 1997
Abstract excerpt
Cyclin E is one of the G1 cyclins that play an important role in cell proliferation. Overexpression of cyclin E protein has been reported in several solid tumors, but little is known about the involvement of cyclin E in leukemia. In this study, we analyzed the expression of cyclin E gene product in 85 patients with acute myelogenous leukemia (AML) by Western blot analysis. In 23 of 85 AML samples (27%), cyclin E...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.