Article
Establishment of functional acinar-like cultures from human salivary glands.
Journal of dental research - 1 Feb 2015
Jang S I, Ong H L, Gallo A, Liu X, Illei G, Alevizos I
Abstract excerpt
Disorders of human salivary glands resulting from therapeutic radiation treatment for head and neck cancers or from the autoimmune disease Sjögren syndrome (SS) frequently result in the reduction or complete loss of saliva secretion. Such irreversible dysfunction of the salivary glands is due to the impairment of acinar cells, the major glandular cells of protein, salt secretion, and fluid movement. Availability...
Topics
- Anoctamin-1
- Aquaporin 5
- Calcium
- Calcium Signaling
- Cell Adhesion Molecules
- Cell Culture Techniques
- Cell Differentiation
- Chloride Channels
- Culture Media
- Cystatin C
- Electric Impedance
- Epithelial Cells
- Homeodomain Proteins
- Humans
