Article
Role of gamma delta T cells in murine collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1993
Peterman G M, Spencer C, Sperling A I, Bluestone J A
Abstract excerpt
Murine collagen-induced arthritis (CIA) is a T cell-mediated disease which is induced by injection of type II collagen. Previous studies have shown that CD4+ cells which express particular V beta TCR genes are involved in the induction of arthritis in this model. In the present report we demonstrate that CD4-, CD8-, TCR gamma delta cells are present in arthritic joints, expanded in peripheral lymphoid tissue of...
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